Shadow's Brilliant Beauties

MACKENZIE&STILES:; Most of the people Stiles knows are were-something or some sort of supernatural. He's very likely to meet Mackenzie - I believe they're going to the same college. Will she be able to handle Stiles' uniqueness? We'll have to see xD
~ Agreed. I wonder how they would react to each other, especially with most of Stiles' friends being some type of were creature. It would be interesting.

MACKENZIE&JACOB:; Jacob's love interest is a werewolf, so if Mackenzie ever tries to hunt/kill Ian, he might try to hex her, which could be interesting! c;
~ She only hunts/kills if the werewolf is in the wrong. She has a code, so as long as his love interest keeps from killing innocents, I don't think she would have any trouble with Jacob. She does dislike Werewolves all together go, regardless of the family code, she does think that all of the were-kind should meet their end due to being more unnatural than most.

KITARIA&ANNA:; Anna's in need of a familiar and if Kitaria doesn't mind a witch who's a couple years younger than her, I think these two would get along nicely.
~She wouldn't mind at all. As long as young Anna has a good head on her shoulders, it would work out splendidly.

CADEN&LLOYD:; Lloyd's totally crushing on Caden's brother AND he's a witch. Bad combo? Good combo? That's up to Caden to decide. When if Lloyd and Xavier start dating, he's going to want Caden's approval. If his crush's boyfriend doesn't like him, I'm not sure what he'd do.
~Oh, what to do about this pair. For one, I am assuming that we are saying Lloyd's crush's brother, not boyfriend. It seems a bit of a typo. XD Anyway, Cade is the older one, therefore far more protective of his brother. If/when Xavier and Lloyd do start dating, Caden would have a hard time swallowing that, especially if he knows that Lloyd is a witch. After all, they are witch hunters. Caden would probably not approve at all and if Lloyd would want Caden's approval, he would have to work at it. However, Caden isn't heartless to his brother's own feelings and if Xavier is fully aware that Lloyd is, infact, a witch and accepts that and still chooses to date him, then Cade would turn a blind eye to the situation and let his brother do as he pleases.

YUKIKO&STILES:; Stiles' only knows two Kitsune - Kira and her mother - so I'd love for him to meet another!
~Um...works for me! XD

BLAZE&ANNA:; Friends? Acquaintances? I think they'd certainly get along.
~Blaze doesn't have too many friends, so it might be a welcomed change of pace for the young druid.

BLAZE&JACOB:; Same for these two. I think they'd get along nicely - perhaps friends?
~Same as above.

BLAZE&LLOYD:; They've probably never talked before, but I think if they ever did acknowledge each other, they'd get along. Might be nice for Blaze to make a senior friend in high school c; Lolol xD
~Lloyd would be a tricky one. He would probably start out trying to be friends with him, but then might distance himself if he finds out that the twins are somehow involved with Lloyd. Blaze has apparently had a bad run in with them and would prefer not to have a repeat of the situation.

Mackenzie && Sam
This could be interesting really. Both hunters, sort of. Sam comes from a family of werewolf hunters. So I would assume that they will at least see each other in the future. Like she shows up at his house & goes on a hunt with his father.
~Agreed. She could possibly go out on hunts with Mr. Miller. Kind of like a back up type of situation. She would most likely see Sam before some of these hunter outings.

UPDATED ~
Niklaus Hart added!